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Thursday, July 23, 2020 | History

4 edition of Lipids, lipoproteins, and drugs found in the catalog.

Lipids, lipoproteins, and drugs

by International Symposium on Drugs Affecting Lipid Metabolism (5th 1974 Milan, Italy)

  • 379 Want to read
  • 1 Currently reading

Published by Plenum Press in New York .
Written in English

    Subjects:
  • Lipids -- Metabolism -- Congresses.,
  • Lipids -- Metabolism -- Disorders -- Congresses.,
  • Drugs -- Physiological effect -- Congresses.,
  • Lipids -- Metabolism -- Congresses.,
  • Lipoproteins -- Metabolism -- Congresses.,
  • Metabolic diseases -- Drug therapy -- Congresses.,
  • Metabolism -- Drug effects -- Congresses.

  • Edition Notes

    Statementedited by David Kritchevsky, Rodolfo Paoletti, and William L. Holmes.
    SeriesAdvances in experimental medicine and biology ;, v. 63
    ContributionsKritchevsky, David, 1920-, Paoletti, Rodolfo., Holmes, William L., 1918-, Società italiana di farmacologia., Fondazione Giovanni Lorenzini., International Society of Biochemical Pharmacology.
    Classifications
    LC ClassificationsQP751 .I64 1974
    The Physical Object
    Paginationxii, 515 p. :
    Number of Pages515
    ID Numbers
    Open LibraryOL5206022M
    ISBN 100306390639
    LC Control Number75031790

    Editor's Note: Commentary based on Wilson DP, Jacobson TA, Jones PH, et al. Use of Lipoprotein(a) in clinical practice: a biomarker whose time has come.A scientific statement from the National Lipid Association. J Clin Lipidol ; Introduction. The traditional lipid profile has served as a mainstay of atherosclerotic cardiovascular disease (ASCVD) risk assessment for decades.   June 9, -- Genetic testing confirms that high levels of a type of cholesterol known as lipoprotein(a) are associated with an increased risk for heart attacks, but the clinical implications of Author: Salynn Boyles.

    In our opinion, available data do not allow us to affirm that low plasma cholesterol levels and the use of cholesterol-lowering drugs may worsen the outcome of patients with COVID Oppositely, a clinical benefit may derive from lowering LDL cholesterol in these conditions, irrespective of the infection-related hypocholesterolemia. The lipoproteins are submicroscopic, macromolecular complexes of lipids (cholesterol, triglycerides, phospholipids) and proteins (apolipoproteins, enzymes), held by non-covalent forces. The basic structure of lipoproteins is a hydrophobic core of triglycerides and/or cholesteryl esters surrounded by a layer of amphipathic phospholipids.

    Beyond the Total, LDL and HDL cholesterol targets, there are a lot of scientific terms used to explain cholesterol. Lipids and lipoproteins are frequently referred to in cholesterol articles Missing: book. Lipid - Lipid - Classification and formation: There are four major classes of circulating lipoproteins, each with its own characteristic protein and lipid composition. They are chylomicrons, very low-density lipoproteins (VLDL), low-density lipoproteins (LDL), and high-density lipoproteins (HDL). Within all these classes of complexes, the various molecular components are not chemically linked Missing: book.


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Lipids, lipoproteins, and drugs by International Symposium on Drugs Affecting Lipid Metabolism (5th 1974 Milan, Italy) Download PDF EPUB FB2

In the lipoproteins of lipoproteins, we have progressed from descriptions of their chemistry to discussion of their physiology and of their control of cholesterol metabolism at the cellular level. Workshop sessions explored thrombosis as affected by drugs, risk factors other than diet, animal models for atherosclerosis research and the organization of lipid clinics and clinical trials.

The book would be essential for laboratories with lipid research programs and for clinical units specializing in and drugs book disorders. For a general reader, it is a useful reference whenever in depth information on lipids and lipoproteins is required." --Clinical Chemistry and Laboratory Medicine/5(2).

Various other drugs have been reported to affect lipid and/or and drugs book levels (Table 4). Lipid changes from these drugs are based on limited data, are reported inconsistently, and could be due to other disease related aspects.

Thus, the effects on serum lipid levels cannot fully be substantiated. Table 4. Antacids. Ascorbic Acid. AspirinCited by: 2. The main types of lipids include fatty acids, phospholipids, triglycerides (TG), and cholesterol (cholesterol esters).

Lipids are vital to normal metabolism and development as they are components of cell membranes, sources of energy, and precursor molecules for synthesis of other compounds, such as steroid hormones and bile acids.

ISBN: OCLC Number: Language Note: English. Description: 1 online resource: Contents: Opening Remarks --Chemistry and Physiology lipoproteins Lipoproteins --The Interaction of Apolipoprotein-Alanine (ApoC-III) with Lipoproteins Study of Structural Features Required for Binding --Lipoproteins and Lipid Transport --Pathways of.

Defining lipid function is a challenging undertaking because of the diversity of the chemical and physical properties of lipids and the fact that each lipid type potentially is involved at various levels of cellular function.

Select CHAPTER 2 - Lipid modifications of proteins. Book chapter Full text access. Biochemistry of Lipids: Lipoproteins and Membranes, Volume Six, contains concise chapters that cover a wide spectrum of topics in the field of lipid biochemistry and cell biology.

It provides an important bridge between broad-based biochemistry textbooks and more technical research publications, offering cohesive, foundational information. Chapter 14 Lipids, lipoproteins and cardiovascular disease Introduction The major lipids present in the plasma are fatty acids, triglycerides, cholesterol and phospholipids.

Other lipid-soluble substances, present in much smaller amounts but of considerable physiological importance, include steroid hormones and fat-soluble vitamins; these are discussed in Chapters 8 respectively.

Abstract. The plasma lipoproteins provide the body with a transport system for the otherwise insoluble lipids. All lipids except for free fatty acids and lysolecithin, circulate in plasma from their site of origin to their site of utilization in association with these lipid-protein complexes, the by: Triglycerides, cholesterol, and phospholipids form lipoproteins when joined with a protein carrier.

Lipoproteins have an inner core that is primarily made up of triglycerides and cholesterol esters (a cholesterol ester is a cholesterol linked to a fatty acid). The outer envelope is made of phospholipids interspersed with proteins and cholesterol.

The Interaction of Apolipoprotein-Alanine (ApoC-III) with Lipids: Study of Structural Features Required for Binding Joel D. Morrisett, Henry J. Pownall, James. Atherosclerosis development requires lipid-carrying particles (lipoproteins) to penetrate the arterial wall.

This is what allows deposits of lipids, cholesterol and other substances to form a plaque. Atherosclerosis can be a precursor to cardiovascular events, including CHD. Lipids Triglycerides are fatty acid esters of glycerol and represent the main lipid component of dietary fat and fat depots of animals.

Cholesterol and triglycerides, being nonpolar lipid substances (insoluble in water), need to be transported in the plasma associated with various lipoprotein by: The other lipoproteins are suspended in serum and must be separated using a centrifuge.

The densest (and smallest) family of particles consists mainly of apoproteins and cholesterol and is called high-density lipoproteins (HDL). Somewhat less dense are the low-density lipoproteins (LDL).

Lipoproteins are simply protein enwrapped lipid transportation vehicles which acquire (lipidate) several lipids namely UC, CE, noncholesterol sterols, TG and PL and transport them to and from various tissues.

Biochemically speaking, lipoproteins are complex structures consisting of a central core of nonpolar (hydrophobic) TG and CE surroundedMissing: book. Take control of your cholesterol with this point plan from nutrition and fitness expert Dr. Janet Brill—without using drugs.

If you are one of the nearly million Americans struggling with high cholesterol, then Dr. Janet Brill offers you a revolutionary new plan for taking control of your health—without the risks of statin drugs/5().

VLDL. LDL and HDL are very low density, low density and high density lipoproteins. LCAT. lecithin-cholesterol acyl transferase. apoproteins refer to the two major apoproteins of HDL, B-apoprotein to the major apoprotein of LDL and C-apoproteins to the three proteins of low molecular weight that are shared between VLDL and HDL in humans and by: Start studying Clinical Chemistry (Lipids and Lipoproteins) jan Learn vocabulary, terms, and more with flashcards, games, and other study tools.

Lipoproteins can be derived from dietary lipids via synthesis in enterocytes of the intestine or from endogenous lipids via synthesis in the liver.

The generalization of lipoprotein types is defined by the amount of protein and lipid as depicted in Table Biochemistry of Lipids: Lipoproteins and Membranes, Volume Six. contains concise chapters that cover a wide spectrum of topics in the field of lipid biochemistry and cell biology.

It provides an important bridge between broad-based biochemistry textbooks and more technical research publications, offering cohesive, foundational information. provides accurate and independent information on more t prescription drugs, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment.

Data sources include IBM Watson Micromedex (updated 4 May ), Cerner Multum™ (updated 4 May ), Wolters Kluwer™. Only free drugs have been believed to be carried into tissues through active or passive transport.

However, considering that lipoproteins function as carriers of serum lipids such as cholesterol Cited by: The high-density lipoproteins (HDL) are often referred to as the “good cholesterol” in contrast to the low- and very-low-density lipoproteins (LDL and VLDL), the “bad cholesterol.” The most important facts about the relatively few drugs in this class are the mechanisms of action.